| Tissue Specificity | Ubiquitously expressed. |
| Post Translational Modifications | |
| Function | Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. |
| Protein Name | S-Methyl-5'-Thioadenosine Phosphorylase5'-Methylthioadenosine PhosphorylaseMta PhosphorylaseMtapMtapase |
| Database Links | Reactome: R-HSA-1237112Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative ELISA Names | S-Methyl-5'-Thioadenosine Phosphorylase ELISA kit5'-Methylthioadenosine Phosphorylase ELISA kitMta Phosphorylase ELISA kitMtap ELISA kitMtapase ELISA kitMTAP ELISA kitMSAP ELISA kit |
| output | |
Information sourced from Uniprot.org
