Human MT3 protein (Recombinant) (His-Tag) (STJP018634)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MT3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MT3 |
| Gene ID | 4504 |
| Uniprot ID | MT3_HUMAN |
| Accession Number | NP_005945.1 |
| Immunogen | Human |
| Immunogen Region | 1-68aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain. |
| Function | Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. |
| Protein Name | Metallothionein-3Mt-3GifbGifGrowth Inhibitory FactorMetallothionein-IiiMt-Iii |
| Database Links | Reactome: R-HSA-5661231 |
| Cellular Localisation | |
| Alternative Protein Names | Metallothionein-3 proteinMt-3 proteinGifb proteinGif proteinGrowth Inhibitory Factor proteinMetallothionein-Iii proteinMt-Iii proteinMT3 protein |
Information sourced from Uniprot.org