Human MS4A1/CD20 protein (Recombinant) (C-His&Avi) {Biotin} (STJP020010)

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STJP020010-100
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Covered by St John's Laboratory Guarantee

Host: E.coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Biotin
Formulation: Supplied as 0.22 Mu m filtered solution in 20 mM PB, 10% Glycerol (pH 7.0).
Storage Instruction: Store at-70 °C. This product is stable at ≤-70 °C for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: MS4A1
Gene ID: 931
Uniprot ID: CD20_HUMAN
Immunogen Region: Ile141-Ser188
Immunogen: Biotinylated Recombinant Human MS4A1/CD20 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ile141-Ser188) of Human MS4A1/CD20 (Accession #P11836-1) fused with a C-His&Avi tag at the C-terminus.
Immunogen Sequence: IKISHFLKMESLNFIRAHTP YINIYNCEPANPSEKNSPST QYCYSIQS
Tissue Specificity Expressed on B-cells.
Post Translational Modifications Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate.
Function B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
Protein Name B-Lymphocyte Antigen Cd20
B-Lymphocyte Surface Antigen B1
Bp35
Leukocyte Surface Antigen Leu-16
Membrane-Spanning 4-Domains Subfamily A Member 1
Cd Antigen Cd20
Database Links
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Lipid-Anchor
Constitutively Associated With Membrane Rafts
Alternative Protein Names B-Lymphocyte Antigen Cd20 protein
B-Lymphocyte Surface Antigen B1 protein
Bp35 protein
Leukocyte Surface Antigen Leu-16 protein
Membrane-Spanning 4-Domains Subfamily A Member 1 protein
Cd Antigen Cd20 protein
MS4A1 protein
CD20 protein

Information sourced from Uniprot.org

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