Human/Mouse/Rat/Equine/Canine MSTN (Growth/Differentiation Factor 8) Sandwich ELISA Kit (STJE0001234)
SPECIFICATIONS
ConjugationBiotin
General Information
| Short Description | This Growth/Differentiation Factor 8 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human/mouse/rat/equine/canine serum, plasma and cell culture supernates. |
| Applications | ELISA |
| Reactivity | Human/Mouse/Rat/Equine/Canine |
| Sensitivity | 28 pg/mL |
| Detection Limit | 625-4000 pg/ml |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Storage Instruction | Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month. |
| Assay Time | 3 hours |
| Detection | Colorimetric |
Target Information
| Gene Symbol | MSTN |
| Gene ID | 2660 |
| Uniprot ID | GDF8_HUMAN |
| Sample Type | serum, plasma and cell culture supernates |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase. |
| Function | Acts specifically as a negative regulator of skeletal muscle growth. |
| Protein Name | Growth/Differentiation Factor 8Gdf-8Myostatin |
| Database Links | Reactome: R-HSA-9617828 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Growth/Differentiation Factor 8 ELISA kitGdf-8 ELISA kitMyostatin ELISA kitMSTN ELISA kitGDF8 ELISA kit |
| output |
Information sourced from Uniprot.org