Post Translational Modifications | The N-terminus is blocked. Extensively N-glycosylated. |
Function | Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein. |
Protein Name | Multimerin-1Emilin-4Elastin Microfibril Interface Located Protein 4Elastin Microfibril Interfacer 4Endothelial Cell Multimerin Cleaved Into - Platelet Glycoprotein Ia* - 155 Kda Platelet MultimerinP-155P155 |
Database Links | Reactome: R-HSA-114608 |
Cellular Localisation | SecretedO-Fucosylation Of Thr-216 And Thr-1055 Is Important For Protein Secretion |
Alternative Protein Names | Multimerin-1 proteinEmilin-4 proteinElastin Microfibril Interface Located Protein 4 proteinElastin Microfibril Interfacer 4 proteinEndothelial Cell Multimerin Cleaved Into - Platelet Glycoprotein Ia* - 155 Kda Platelet Multimerin proteinP-155 proteinP155 proteinMMRN1 proteinECM proteinEMILIN4 proteinGPIA* proteinMMRN protein |
Information sourced from Uniprot.org