| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor. |
| Protein Name | Max Gene-Associated ProteinMax Dimerization Protein 5 |
| Database Links | Reactome: R-HSA-8953750 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Max Gene-Associated Protein ELISA kitMax Dimerization Protein 5 ELISA kitMGA ELISA kitKIAA0518 ELISA kitMAD5 ELISA kit |
| output | |
Information sourced from Uniprot.org
