Human MFSD2A (Major Facilitator Superfamily Domain Containing Protein 2A) Sandwich ELISA Kit Kit (STJE0010571)

Human MFSD2A (Major Facilitator Superfamily Domain Containing Protein 2A) Sandwich ELISA Kit Kit (STJE0010571)

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STJE0010571
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.114ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This MFSD2A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: MFSD2A
Gene ID: 84879
Uniprot ID: NLS1_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity In placenta, associated with trophoblast cells.
Post Translational Modifications
Function Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis. Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion.
Protein Name Sodium-Dependent Lysophosphatidylcholine Symporter 1
Nls1
Sodium-Dependent Lpc Symporter 1
Major Facilitator Superfamily Domain-Containing Protein 2a
Hsmfsd2a
Mfsd2a
Database Links Reactome: R-HSA-1483191
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Endoplasmic Reticulum Membrane
Cytoplasmic Punctae That May Represent Vesicles Shuttling Between The Endoplasmic Reticulum And The Plasma Membrane
Alternative ELISA Names Sodium-Dependent Lysophosphatidylcholine Symporter 1 ELISA kit
Nls1 ELISA kit
Sodium-Dependent Lpc Symporter 1 ELISA kit
Major Facilitator Superfamily Domain-Containing Protein 2a ELISA kit
Hsmfsd2a ELISA kit
Mfsd2a ELISA kit
MFSD2A ELISA kit
MFSD2 ELISA kit
NLS1 ELISA kit
HMFN0656 ELISA kit
PP9177 ELISA kit
UNQ300 ELISA kit
PRO341 ELISA kit
output

Information sourced from Uniprot.org

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