Human MFGE8 (Lactadherin) Antibody Pair (STJAP00503)
SPECIFICATIONS
HostSheep/Sheep
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Human MFGE8 protien.Detection Immunogen: Recombinant Human MFGE8 protien.
General Information
| Short Description | This MFGE8 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Sheep/Sheep |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | MFGE8 |
| Gene ID | 4240 |
| Uniprot ID | MFGM_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human MFGE8 protien.Detection Immunogen: Recombinant Human MFGE8 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273. |
| Function | Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Medin: Main constituent of aortic medial amyloid. |
| Protein Name | LactadherinBreast Epithelial Antigen Ba46HmfgMfgmMilk Fat Globule-Egf Factor 8Mfg-E8Sed1 Cleaved Into - Lactadherin Short Form - Medin |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275Reactome: R-HSA-977225 |
| Cellular Localisation | MembranePeripheral Membrane ProteinSecretedCytoplasmic VesicleSecretory VesicleAcrosome MembraneLocated In The Acrosomal Region Of Zona-Pellucida Bound Sperm |
| Alternative Antibody Pair Names | Lactadherin antibody pairBreast Epithelial Antigen Ba46 antibody pairHmfg antibody pairMfgm antibody pairMilk Fat Globule-Egf Factor 8 antibody pairMfg-E8 antibody pairSed1 Cleaved Into - Lactadherin Short Form - Medin antibody pairMFGE8 antibody pair |
Information sourced from Uniprot.org