Human Methionine Aminopeptidase 1D protein (Recombinant) (His-Tag) (STJP018567)

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STJP018567
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Methionine Aminopeptidase 1D-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% Glycerol, 1mM DTT
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: METAP1D
Gene ID: 254042
Uniprot ID: MAP12_HUMAN
Immunogen Region: 20-335aa
Accession Number: NP_954697
Immunogen: Human
Immunogen Sequence: SSPLNHI YLHKQSSSQQ RRNFFFRRQR DISHSIVLPA AVSSAHPVPK HIKKPDYVTT GIVPDWGDSI EVKNEDQIQG LHQACQLARH VLLLAGKSLK VDMTTEEIDA LVHREIISHN AYPSPLGYGG FPKSVCTSVN NVLCHGIPDS RPLQDGDIIN IDVTVYYNGY HGDTSETFLV GNVDECGKKL VEVARRCRDE AIAACR
Tissue Specificity Overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level).
Function Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. May play a role in colon tumorigenesis.
Protein Name Methionine Aminopeptidase 1d - Mitochondrial
Map 1d
Metap 1d
Methionyl Aminopeptidase Type 1d - Mitochondrial
Peptidase M 1d
Database Links
Cellular Localisation Mitochondrion
Alternative Protein Names Methionine Aminopeptidase 1d - Mitochondrial protein
Map 1d protein
Metap 1d protein
Methionyl Aminopeptidase Type 1d - Mitochondrial protein
Peptidase M 1d protein
METAP1D protein
MAP1D protein

Information sourced from Uniprot.org

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