• Human Mesothelin/MSLN protein (Recombinant) (C-hFc&His) (STJP001231)
  • Human Mesothelin/MSLN protein (Recombinant) (C-hFc&His) (STJP001231)
  • Human Mesothelin/MSLN protein (Recombinant) (C-hFc&His) (STJP001231)
  • Human Mesothelin/MSLN protein (Recombinant) (C-hFc&His) (STJP001231)
  • Human Mesothelin/MSLN protein (Recombinant) (C-hFc&His) (STJP001231)
  • Human Mesothelin/MSLN protein (Recombinant) (C-hFc&His) (STJP001231)

Human Mesothelin/MSLN protein (Recombinant) (C-hFc&His) (STJP001231)

SKU:
STJP001231

£63.50 - £223.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Mesothelin/MSLN-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Loaded Human Mesothelin/MSLN Protein, C-hFc&His on ProA Biosensor, can bind Human CA125 Protein, C-His&Avi with an affinity constant of 17.2 nM as determined in BLI assay (Gator).
Gene Symbol: MSLN
Gene ID: 10232
Uniprot ID: MSLN_HUMAN
Immunogen: Recombinant Human Mesothelin/MSLN Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu296-Gly580) of human Mesothelin (Accession #NP_005814.2) fused with a Fc, 6×His tag at the C-terminus.
Post Translational Modifications Both MPF and the cleaved form of mesothelin are N-glycosylated. Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.
Function Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
Protein Name Mesothelin
Cak1 Antigen
Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor
Mpf - Mesothelin - Cleaved Form
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Golgi Apparatus
Megakaryocyte-Potentiating Factor: Secreted
Isoform 3: Secreted
Alternative Protein Names Mesothelin protein
Cak1 Antigen protein
Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor protein
Mpf - Mesothelin - Cleaved Form protein
MSLN protein
MPF protein

Information sourced from Uniprot.org

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