Human MCL1 protein (Recombinant) (N-His) (STJP005220)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MCL1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | MCL1 |
| Gene ID | 4170 |
| Uniprot ID | MCL1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg6-Ile328 |
Additional Info
| Function | Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis. |
| Protein Name | Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1Bcl-2-Like Protein 3Bcl2-L-3Bcl-2-Related Protein Eat/Mcl1Mcl1/Eat |
| Database Links | Reactome: R-HSA-6785807Reactome: R-HSA-9725370 |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinCytoplasmMitochondrionNucleusNucleoplasmCytoplasmicAssociated With Mitochondria |
| Alternative Protein Names | Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 proteinBcl-2-Like Protein 3 proteinBcl2-L-3 proteinBcl-2-Related Protein Eat/Mcl1 proteinMcl1/Eat proteinMCL1 proteinBCL2L3 protein |
Information sourced from Uniprot.org