Human MCL1 protein (Recombinant) (N-His) (STJP005220)

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STJP005220
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MCL1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MCL1
Gene ID: 4170
Uniprot ID: MCL1_HUMAN
Immunogen Region: Arg6-Ile328
Immunogen: Homo sapiens (Human)
Function Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Protein Name Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
Bcl-2-Like Protein 3
Bcl2-L-3
Bcl-2-Related Protein Eat/Mcl1
Mcl1/Eat
Database Links Reactome: R-HSA-6785807
Reactome: R-HSA-9725370
Cellular Localisation Membrane
Single-Pass Membrane Protein
Cytoplasm
Mitochondrion
Nucleus
Nucleoplasm
Cytoplasmic
Associated With Mitochondria
Alternative Protein Names Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 protein
Bcl-2-Like Protein 3 protein
Bcl2-L-3 protein
Bcl-2-Related Protein Eat/Mcl1 protein
Mcl1/Eat protein
MCL1 protein
BCL2L3 protein

Information sourced from Uniprot.org

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