Human MBP-C (Mannose-Binding Protein C) Antibody Pair (STJAP00246)

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STJAP00246-50
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Host: Goat/Goat
Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This MBP-C antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Polyclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Antigen Affinity.
Detection Purification: Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: MBL2
Gene ID: 4153
Uniprot ID: MBL2_HUMAN
Immunogen: Capture immunogen: Recombinant Human MBP-C protein.
Detection Immunogen: Recombinant Human MBP-C protein.
Function Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. Upon SARS coronavirus-2/SARS-CoV-2 infection, activates the complement lectin pathway which leads to the inhibition SARS-CoV-2 infection and a reduction of the induced inflammatory response.
Protein Name Mannose-Binding Protein C
Mbp-C
Collectin-1
Mbp1
Mannan-Binding Protein
Mannose-Binding Lectin
Database Links Reactome: R-HSA-166662
Reactome: R-HSA-166663
Reactome: R-HSA-9705671
Cellular Localisation Secreted
Alternative Antibody Pair Names Mannose-Binding Protein C antibody pair
Mbp-C antibody pair
Collectin-1 antibody pair
Mbp1 antibody pair
Mannan-Binding Protein antibody pair
Mannose-Binding Lectin antibody pair
MBL2 antibody pair
COLEC1 antibody pair
MBL antibody pair

Information sourced from Uniprot.org

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