Human MAPRE3 protein (Recombinant) (His-Tag) (STJP016886)

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STJP016886
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MAPRE3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 2mM DTT, 0.1M NaCl.
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAPRE3
Gene ID: 22924
Uniprot ID: MARE3_HUMAN
Immunogen Region: 1-281aa
Accession Number: NP_036458
Immunogen: Human
Immunogen Sequence: MAVNVYSTSV TSENLSRHDM LAWVNDSLHL NYTKIEQLCS GAAYCQFMDM LFPGCVHLRK VKFQAKLEHE YIHNFKVLQA AFKKMGVDKI IPVEKLVKGK FQDNFEFIQW FKKFFDANYD GKDYNPLLAR QGQDVAPPPN PGDQIFNKSK KLIGTAVPQR TSPTGPKNMQ TSGRLSNVAP PCILRKNPPS ARNGGHETDA QILELN
Tissue Specificity Predominantly expressed in brain and muscle.
Function Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules.
Protein Name Microtubule-Associated Protein Rp/Eb Family Member 3
Eb1 Protein Family Member 3
Ebf3
End-Binding Protein 3
Eb3
Rp3
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Associated With The Microtubule Network
Detected At The Plus End Of Microtubules
Alternative Protein Names Microtubule-Associated Protein Rp/Eb Family Member 3 protein
Eb1 Protein Family Member 3 protein
Ebf3 protein
End-Binding Protein 3 protein
Eb3 protein
Rp3 protein
MAPRE3 protein

Information sourced from Uniprot.org

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