Human MAP2 (Microtubule Associated Protein 2) Sandwich ELISA Kit (STJE0010477)

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STJE0010477
€485.40 - €675.00
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Short Description :This MAP2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Applications:ELISA
Reactivity:Human
Sensitivity:6.3pg/mL
Detection Limit:15.6-1000pg/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:MAP2
Gene ID:4133
Uniprot ID:MTAP2_HUMAN
Sample Type:serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly. Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67. The interaction with KNDC1 enhances MAP2 threonine phosphorylation.
Function The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Protein Name Microtubule-Associated Protein 2
Map-2
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Dendrite
Alternative ELISA Names Microtubule-Associated Protein 2 ELISA kit
Map-2 ELISA kit
MAP2 ELISA kit
output

Information sourced from Uniprot.org