Human MAGEC2 protein (Recombinant) (N-His) (STJP008006)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MAGEC2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | MAGEC2 |
| Gene ID | 51438 |
| Uniprot ID | MAGC2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp132-Ser328 |
Additional Info
| Function | Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. |
| Protein Name | Melanoma-Associated Antigen C2Cancer/Testis Antigen 10Ct10Hepatocellular Carcinoma-Associated Antigen 587Mage-C2 AntigenMage-E1 Antigen |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusNuclear In Germ CellsCytoplasmic In Well-Differentiated Hepatocellular CarcinomaNuclear In Moderately- And Poorly-Differentiated Hepatocellular Carcinoma |
| Alternative Protein Names | Melanoma-Associated Antigen C2 proteinCancer/Testis Antigen 10 proteinCt10 proteinHepatocellular Carcinoma-Associated Antigen 587 proteinMage-C2 Antigen proteinMage-E1 Antigen proteinMAGEC2 proteinHCA587 proteinMAGEE1 protein |
Information sourced from Uniprot.org