Human MAGEC2 protein (Recombinant) (N-His) (STJP008006)

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STJP008006
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MAGEC2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MAGEC2
Gene ID: 51438
Uniprot ID: MAGC2_HUMAN
Immunogen Region: Asp132-Ser328
Immunogen: Homo sapiens (Human)
Function Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Protein Name Melanoma-Associated Antigen C2
Cancer/Testis Antigen 10
Ct10
Hepatocellular Carcinoma-Associated Antigen 587
Mage-C2 Antigen
Mage-E1 Antigen
Cellular Localisation Cytoplasm
Nucleus
Nuclear In Germ Cells
Cytoplasmic In Well-Differentiated Hepatocellular Carcinoma
Nuclear In Moderately- And Poorly-Differentiated Hepatocellular Carcinoma
Alternative Protein Names Melanoma-Associated Antigen C2 protein
Cancer/Testis Antigen 10 protein
Ct10 protein
Hepatocellular Carcinoma-Associated Antigen 587 protein
Mage-C2 Antigen protein
Mage-E1 Antigen protein
MAGEC2 protein
HCA587 protein
MAGEE1 protein

Information sourced from Uniprot.org

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