Human LYPLA2 protein (Recombinant) (N-His) (STJP003423)

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STJP003423
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LYPLA2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: LYPLA2
Gene ID: 11313
Uniprot ID: LYPA2_HUMAN
Immunogen Region: Met1-Thr196
Immunogen: Homo sapiens (Human)
Function Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.
Protein Name Acyl-Protein Thioesterase 2
Apt-2
Lysophospholipase Ii
Lpl-Ii
Lysopla Ii
Palmitoyl-Protein Hydrolase
Database Links Reactome: R-HSA-373760
Cellular Localisation Cytoplasm
Alternative Protein Names Acyl-Protein Thioesterase 2 protein
Apt-2 protein
Lysophospholipase Ii protein
Lpl-Ii protein
Lysopla Ii protein
Palmitoyl-Protein Hydrolase protein
LYPLA2 protein
APT2 protein

Information sourced from Uniprot.org

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