Human Lumican/LUM protein (Recombinant) (C-His) (STJP000987)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Lumican/LUM Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln19-Asn338) of human Lumican/LUM (Accession #NP_002336.1) fused with a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Lumican/LUM-C-His protein was developed in hek293 cells using the region Gln19-Asn338. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | LUM |
| Gene ID | 4060 |
| Uniprot ID | LUM_HUMAN |
| Immunogen | Recombinant Human Lumican/LUM Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln19-Asn338) of human Lumican/LUM (Accession #NP_002336.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Region | Gln19-Asn338 |
| Immunogen Sequence | QYYDYDFPLSIYGQSSPNCA PECNCPESYPSAMYCDELKL KSVPMVPPGIKYLYLRNNQI DHIDEKAFENVTDLQWLILD HNLLENSKIKGRVFSKLKQL KKLHINHNNLTESVGPLPKS LEDLQLTHNKITKLGSFEGL VNLTFIHLQHNRLKEDAVSA AFKGLKSLEYLDLSFNQIAR LPSGLPVSLLTLYLDNNKIS NIPDEYFKRFNALQYLRLSH NELADSGIPGNSFNVSSLV |
Additional Info
| Tissue Specificity | Cornea and other tissues. |
| Post Translational Modifications | Sulfated on tyrosine residue(s). Contains keratan sulfate. |
| Protein Name | LumicanKeratan Sulfate Proteoglycan LumicanKspg Lumican |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-2022857Reactome: R-HSA-216083Reactome: R-HSA-3000178Reactome: R-HSA-3656225Reactome: R-HSA-3656243Reactome: R-HSA-3656244 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Lumican proteinKeratan Sulfate Proteoglycan Lumican proteinKspg Lumican proteinLUM proteinLDC proteinSLRR2D protein |
Information sourced from Uniprot.org