Human LSM5 protein (Recombinant) (His-Tag) (STJP018478)

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STJP018478
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Short Description :Recombinant-Human LSM5-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.5) containing 10% Glycerol, 0.15M NaCl, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:LSM5
Gene ID:23658
Uniprot ID:LSM5_HUMAN
Accession Number:NP_036454
Immunogen:Human
Immunogen Region:1-91aa
Immunogen Sequence:MAANATT NPSQLLPLEL VDKCIGSRIH IVMKSDKEIV GTLLGFDDFV NMVLEDVTEF EITPEGRRIT KLDQILLNGN NITMLVPGGE GPEV
Function Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
Protein Name U6 Snrna-Associated Sm-Like Protein Lsm5
Database Links Reactome: R-HSA-430039
Reactome: R-HSA-72163
Cellular Localisation Nucleus
Alternative Protein Names U6 Snrna-Associated Sm-Like Protein Lsm5 protein
LSM5 protein

Information sourced from Uniprot.org