| Short Description : | Recombinant-Human LSM4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LSM4 |
| Gene ID: | 25804 |
| Uniprot ID: | LSM4_HUMAN |
| Accession Number: | NP_036453 |
| Immunogen: | Human |
| Immunogen Region: | 1-139aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MLPLSLLKTA QNHPMLVELK NGETYNGHLV SCDNWMNINL REVICTSRDG DKFWRMPECY IRGSTIKYLR IPDEIIDMVK EEVVAKGRGR GGLQQQKQQK GRGMGGAGRG VFGGRGRGGI PGTGRGQPEK KPGRQAGKQ |
| Function | Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. |
| Protein Name | U6 Snrna-Associated Sm-Like Protein Lsm4Glycine-Rich ProteinGrp |
| Database Links | Reactome: R-HSA-430039Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | U6 Snrna-Associated Sm-Like Protein Lsm4 proteinGlycine-Rich Protein proteinGrp proteinLSM4 protein |
Information sourced from Uniprot.org
