| Short Description : | Recombinant-Human LRRTM2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | LRRTM2 |
| Gene ID: | 26045 |
| Uniprot ID: | LRRT2_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Cys34-Arg422 |
| Function | Involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B. |
| Protein Name | Leucine-Rich Repeat Transmembrane Neuronal Protein 2Leucine-Rich Repeat Neuronal 2 Protein |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPostsynaptic Cell MembraneLocalized To Excitatory Synapses |
| Alternative Protein Names | Leucine-Rich Repeat Transmembrane Neuronal Protein 2 proteinLeucine-Rich Repeat Neuronal 2 Protein proteinLRRTM2 proteinKIAA0416 proteinLRRN2 protein |
Information sourced from Uniprot.org