Human LRRFIP1 (Leucine Rich Repeat In FLII Interacting Protein 1) Sandwich ELISA Kit (STJE0010429)
SPECIFICATIONS
General Information
| Short Description | This LRRFIP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.127ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | LRRFIP1 |
| Gene ID | 9208 |
| Uniprot ID | LRRF1_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Post Translational Modifications | |
| Function | Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. |
| Protein Name | Leucine-Rich Repeat Flightless-Interacting Protein 1Lrr Flii-Interacting Protein 1Gc-Binding Factor 2Tar Rna-Interacting Protein |
| Database Links | Reactome: R-HSA-1839117Reactome: R-HSA-3134973Reactome: R-HSA-5655302 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative ELISA Names | Leucine-Rich Repeat Flightless-Interacting Protein 1 ELISA kitLrr Flii-Interacting Protein 1 ELISA kitGc-Binding Factor 2 ELISA kitTar Rna-Interacting Protein ELISA kitLRRFIP1 ELISA kitGCF2 ELISA kitTRIP ELISA kit |
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Information sourced from Uniprot.org