Human LPO protein (Recombinant) (N-His) (STJP004338)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LPO-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | LPO |
| Gene ID | 4025 |
| Uniprot ID | PERL_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Val283-Asn712 |
Additional Info
| Function | Heme-containing oxidoreductase which catalyzes the conversion of thiocyanate (SCN(-)) into antimicrobial agent hypothiocyanous acid (OSCN(-)) in the presence of hydrogen peroxide (H2O2). Also involved in the conversion of iodide (I(-)) into hypoiodite (IO(-)) in the presence of H2O2. Responsible for the inactivation of a wide range of micro-organisms and hence, important component of defense mechanism. Shows antibacterial properties against Pseudomonas aeruginosa. The lactoperoxidase-SCN(-)-H2O2 system shows antibacterial properties against Burkholderia cepacia and Haemophilus influenzae in vitro. Present in mammary and salivary gland secretions and may contribute to airway host defense against infection. May contribute to maintaining an appropriate H2O2 cellular level, therefore protecting cells from H2O2-caused injuries and inflammation. |
| Protein Name | LactoperoxidaseLpoSalivary PeroxidaseSpo |
| Database Links | Reactome: R-HSA-8941413 |
| Cellular Localisation | SecretedCytoplasm |
| Alternative Protein Names | Lactoperoxidase proteinLpo proteinSalivary Peroxidase proteinSpo proteinLPO proteinSAPX protein |
Information sourced from Uniprot.org