Human LPCAT1 protein (Recombinant) (N-His) (STJP015231)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LPCAT1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | LPCAT1 |
| Gene ID | 79888 |
| Uniprot ID | PCAT1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr310-Thr496 |
Additional Info
| Function | Exhibits acyltransferase activity. Exhibits acetyltransferase activity. Activity is calcium-independent. Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. Involved in the regulation of lipid droplet number and size. |
| Protein Name | Lysophosphatidylcholine Acyltransferase 1Lpc Acyltransferase 1Lpcat-1Lysopc Acyltransferase 11-Acylglycerol-3-Phosphate O-Acyltransferase1-Acylglycerophosphocholine O-Acyltransferase1-Alkenylglycerophosphocholine O-Acyltransferase1-Alkylglycerophosphocholine O-AcetyltransferaseAcetyl-Coa -Lyso-Platelet-Activating Factor AcetyltransferaseAcetyl-Coa -Lyso-Paf AcetyltransferaseLyso-Paf AcetyltransferaseLysopafatAcyltransferase-Like 2Phosphonoformate Immuno-Associated Protein 3 |
| Database Links | Reactome: R-HSA-1482788Reactome: R-HSA-1482925Reactome: R-HSA-1483166Reactome: R-HSA-1483191Reactome: R-HSA-6798695 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinGolgi Apparatus MembraneCell MembraneLipid DropletMay Adopt A Monotopic Topology When Embedded In The Lipid Monolayer Of The Lipid DropletWith Both Termini Exposed To The Cytoplasm |
| Alternative Protein Names | Lysophosphatidylcholine Acyltransferase 1 proteinLpc Acyltransferase 1 proteinLpcat-1 proteinLysopc Acyltransferase 1 protein1-Acylglycerol-3-Phosphate O-Acyltransferase protein1-Acylglycerophosphocholine O-Acyltransferase protein1-Alkenylglycerophosphocholine O-Acyltransferase protein1-Alkylglycerophosphocholine O-Acetyltransferase proteinAcetyl-Coa -Lyso-Platelet-Activating Factor Acetyltransferase proteinAcetyl-Coa -Lyso-Paf Acetyltransferase proteinLyso-Paf Acetyltransferase proteinLysopafat proteinAcyltransferase-Like 2 proteinPhosphonoformate Immuno-Associated Protein 3 proteinLPCAT1 proteinAYTL2 proteinPFAAP3 protein |
Information sourced from Uniprot.org