| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Immunoreactivity: | Measured by its ability to inhibit active Cathepsin V cleavage of a fluorogenic peptide substrate Z-LR-AMC. The IC50 value is <2.94 nM. |
| Gene Symbol: | LCN1 |
| Gene ID: | 3933 |
| Uniprot ID: | LCN1_HUMAN |
| Immunogen: | Recombinant Human Lipocalin-1/LCN1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (His19-Asp176) of human Lipocalin-1/LCN1 (Accession #NP_002288.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | HHLLASDEEIQDVSGTWYLK AMTVDREFPEMNLESVTPMT LTTLEGGNLEAKVTMLISGR CQEVKAVLEKTDEPGKYTAD GGKHVAYIIRSHVKDHYIFY CEGELHGKPVRGVKLVGRDP KNNLEALEDFEKAAGARGLS TESILIPRQSETCSPGSD |
| Function | Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. |
| Protein Name | Lipocalin-1Tear LipocalinTlcTear PrealbuminTpVon Ebner Gland ProteinVeg Protein |
| Database Links | Reactome: R-HSA-804914 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Lipocalin-1 proteinTear Lipocalin proteinTlc proteinTear Prealbumin proteinTp proteinVon Ebner Gland Protein proteinVeg Protein proteinLCN1 proteinVEGP protein |
Information sourced from Uniprot.org