Human LIMP II/SCARB2/CD36L2 protein (Recombinant) (C-hFc&His) (STJP000862)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human LIMP II/SCARB2/CD36L2 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Arg27-Thr432) of human LIMPII/SR-B2 (Accession #NP_005497.1) fused with an Fc, 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human LIMP II/SCARB2/CD36L2-C-hFc&His protein was developed in hek293 cells using the region Arg27-Thr432. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA. Immobilized Human LDLR/LDL Receptor at 4 Mu g/mL (100 Mu L/well) can bind Human SCARB2 with a linear range of 0.016-3.79 Mu g/mL. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | SCARB2 |
| Gene ID | 950 |
| Uniprot ID | SCRB2_HUMAN |
| Immunogen | Recombinant Human LIMP II/SCARB2/CD36L2 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Arg27-Thr432) of human LIMPII/SR-B2 (Accession #NP_005497.1) fused with an Fc, 6×His tag at the C-terminus. |
| Immunogen Region | Arg27-Thr432 |
| Immunogen Sequence | RVFQKAVDQSIEKKIVLRNG TEAFDSWEKPPLPVYTQFYF FNVTNPEEILRGETPRVEEV GPYTYRELRNKANIQFGDNG TTISAVSNKAYVFERDQSVG DPKIDLIRTLNIPVLTVIEW SQVHFLREIIEAMLKAYQQK LFVTHTVDELLWGYKDEILS LIHVFRPDISPYFGLFYEKN GTNDGDYVFLTGEDSYLNFT KIVEWNGKTSLDWWITDKCN MINGTDGDSFHPLITKDEV |
Additional Info
| Function | Acts as a lysosomal receptor for glucosylceramidase (GBA1) targeting. (Microbial infection) Acts as a receptor for enterovirus 71. |
| Protein Name | Lysosome Membrane Protein 285 Kda Lysosomal Membrane SialoglycoproteinLgp85Cd36 Antigen-Like 2Lysosome Membrane Protein IiLimp IiScavenger Receptor Class B Member 2Cd Antigen Cd36 |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Lysosome Membrane Protein 2 protein85 Kda Lysosomal Membrane SialoglycoproteinLgp85 proteinCd36 Antigen-Like 2 proteinLysosome Membrane Protein Ii proteinLimp Ii proteinScavenger Receptor Class B Member 2 proteinCd Antigen Cd36 proteinSCARB2 proteinCD36L2 proteinLIMP2 proteinLIMPII protein |
Information sourced from Uniprot.org