• Human LILRB3/ILT-5/CD85a protein (Recombinant) (C-His&Avi) (STJP001428)

Human LILRB3/ILT-5/CD85a protein (Recombinant) (C-His&Avi) (STJP001428)

SKU:
STJP001428

£76.50 - £248.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human LILRB3/ILT-5/CD85a-C-His&Avi protein was developed from hek293 cells and has a target region of C-His&Avi. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Gene Symbol: LILRB3
Gene ID: 102725035/107987462
Uniprot ID: LIRB3_HUMAN
Immunogen: Recombinant Human LILRB3/ILT-5/CD85a Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Glu443) of human LILRB3/CD85a/ILT5 (Accession #XP_016885786.1) fused with a 6×His, Avi tag at the C-termi
Post Translational Modifications Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-595 and Tyr-625 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2.
Function May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3
Lir-3
Leukocyte Immunoglobulin-Like Receptor 3
Cd85 Antigen-Like Family Member A
Immunoglobulin-Like Transcript 5
Ilt-5
Monocyte Inhibitory Receptor Hl9
Cd Antigen Cd85a
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 protein
Lir-3 protein
Leukocyte Immunoglobulin-Like Receptor 3 protein
Cd85 Antigen-Like Family Member A protein
Immunoglobulin-Like Transcript 5 protein
Ilt-5 protein
Monocyte Inhibitory Receptor Hl9 protein
Cd Antigen Cd85a protein
LILRB3 protein
ILT5 protein
LIR3 protein

Information sourced from Uniprot.org

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