• Human LILRB2/ILT-4/CD85d protein (Recombinant) (C-hFc&His) (STJP001364)
  • Human LILRB2/ILT-4/CD85d protein (Recombinant) (C-hFc&His) (STJP001364)
  • Human LILRB2/ILT-4/CD85d protein (Recombinant) (C-hFc&His) (STJP001364)
  • Human LILRB2/ILT-4/CD85d protein (Recombinant) (C-hFc&His) (STJP001364)

Human LILRB2/ILT-4/CD85d protein (Recombinant) (C-hFc&His) (STJP001364)

SKU:
STJP001364

£72.50 - £223.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human LILRB2/ILT-4/CD85d-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human LILRB2 Protein at 1 Mu g/mL (100 Mu L/well) can bind LILRB2 Rabbit pAb with a linear range of 0.03-6.78 ng/mL.
Gene Symbol: LILRB2
Gene ID: 10288
Uniprot ID: LIRB2_HUMAN
Immunogen: Recombinant Human LILRB2/ILT-4/CD85d Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln22-Val461) of human LILRB2/CD85d/ILT4 (Accession #AAH36827.1) fused with a Fc, 6×His tag at the C-terminus.
Post Translational Modifications Phosphorylated on tyrosine residues. Dephosphorylated by PTPN6.
Function Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2
Lir-2
Leukocyte Immunoglobulin-Like Receptor 2
Cd85 Antigen-Like Family Member D
Immunoglobulin-Like Transcript 4
Ilt-4
Monocyte/Macrophage Immunoglobulin-Like Receptor 10
Mir-10
Cd Antigen Cd85d
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 protein
Lir-2 protein
Leukocyte Immunoglobulin-Like Receptor 2 protein
Cd85 Antigen-Like Family Member D protein
Immunoglobulin-Like Transcript 4 protein
Ilt-4 protein
Monocyte/Macrophage Immunoglobulin-Like Receptor 10 protein
Mir-10 protein
Cd Antigen Cd85d protein
LILRB2 protein
ILT4 protein
LIR2 protein
MIR10 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance