Human LILRA3 (Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016732)
SPECIFICATIONS
General Information
| Short Description | This LILRA3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.117ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | LILRA3 |
| Gene ID | 11026 |
| Uniprot ID | LIRA3_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung. |
| Post Translational Modifications | N-glycosylation is required for ligand binding. |
| Function | Acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes. |
| Protein Name | Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3Cd85 Antigen-Like Family Member EImmunoglobulin-Like Transcript 6Ilt-6Leukocyte Immunoglobulin-Like Receptor 4Lir-4Monocyte Inhibitory Receptor Hm43/Hm31Cd Antigen Cd85e |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 ELISA kitCd85 Antigen-Like Family Member E ELISA kitImmunoglobulin-Like Transcript 6 ELISA kitIlt-6 ELISA kitLeukocyte Immunoglobulin-Like Receptor 4 ELISA kitLir-4 ELISA kitMonocyte Inhibitory Receptor Hm43/Hm31 ELISA kitCd Antigen Cd85e ELISA kitLILRA3 ELISA kitILT6 ELISA kitLIR4 ELISA kit |
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Information sourced from Uniprot.org