Human LILRA3/ILT-6/CD85e protein (Recombinant) (C-His&Avi) {Biotin} (STJP020240)

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STJP020240-100
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Short Description :Recombinant-Human LILRA3/ILT-6/CD85e-C-His&Avi protein was developed in hek293 cells using the region Gly24-Glu439. For use in research applications.
Host:HEK293 cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Biotin
Formulation:Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization. Contact us for customized product form or formulation.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:< 1 EU/Mu g of the protein by LAL method.
Gene Symbol:LILRA3
Gene ID:11026
Uniprot ID:LIRA3_HUMAN
Immunogen:Biotinylated Recombinant Human LILRA3/ILT-6/CD85e Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Glu439) of Human LILRA3/ILT-6/CD85e (Accession #) fused with His tag and Avi Tag at the C-te
Immunogen Region:Gly24-Glu439
Tissue Specificity Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung.
Post Translational Modifications N-glycosylation is required for ligand binding.
Function Acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3
Cd85 Antigen-Like Family Member E
Immunoglobulin-Like Transcript 6
Ilt-6
Leukocyte Immunoglobulin-Like Receptor 4
Lir-4
Monocyte Inhibitory Receptor Hm43/Hm31
Cd Antigen Cd85e
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Protein Names Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 protein
Cd85 Antigen-Like Family Member E protein
Immunoglobulin-Like Transcript 6 protein
Ilt-6 protein
Leukocyte Immunoglobulin-Like Receptor 4 protein
Lir-4 protein
Monocyte Inhibitory Receptor Hm43/Hm31 protein
Cd Antigen Cd85e protein
LILRA3 protein
ILT6 protein
LIR4 protein

Information sourced from Uniprot.org

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