Name: Human LILRA3/CD85e protein (Recombinant) (C-His) (STJP001323)
SKU: STJP001323
Availability: InStock

Human LILRA3/CD85e protein (Recombinant) (C-His) (STJP001323)

SKU:

STJP001323

£97.50 - £291.50

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	<1 EU/Mu g

Gene Symbol:	LILRA3
Gene ID:	11026
Uniprot ID:	LIRA3_HUMAN
Immunogen:	Recombinant Human LILRA3/CD85e Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Glu439) of Human LILRA3 (Accession #NP_006856.3) fused with a 6×His tag at the C-terminus.
Immunogen Sequence:	GPLPKPTLWAEPGSVITQGS PVTLRCQGSLETQEYHLYRE KKTALWITRIPQELVKKGQF PILSITWEHAGRYCCIYGS HTAGLSESSDPLELVVTGAY SKPTLSALPSPVVTSGGNVT I QCDSQVAFDGFILCKEGE DEHPQCLNSHSHARGSSRAI FSVGPVSPSRRWSYRCYGYD SR APYVWSLPSDLLGLLVP GVSKKPSLSVQPGPVVAPGE KLTFQCGSDAGYDRFVLYKE

Post Translational Modifications	N-glycosylation is required for ligand binding.
Function	Acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
Protein Name	Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 Cd85 Antigen-Like Family Member E Immunoglobulin-Like Transcript 6 Ilt-6 Leukocyte Immunoglobulin-Like Receptor 4 Lir-4 Monocyte Inhibitory Receptor Hm43/Hm31 Cd Antigen Cd85e
Database Links	Reactome: R-HSA-198933 Reactome: R-HSA-6798695
Cellular Localisation	Secreted
Alternative Protein Names	Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 protein Cd85 Antigen-Like Family Member E protein Immunoglobulin-Like Transcript 6 protein Ilt-6 protein Leukocyte Immunoglobulin-Like Receptor 4 protein Lir-4 protein Monocyte Inhibitory Receptor Hm43/Hm31 protein Cd Antigen Cd85e protein LILRA3 protein ILT6 protein LIR4 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP001688	Human LILRA3/CD85e protein (Recombinant) (C-His-Avi) {Biotin} (STJP001688)	HEK293
STJP001209	Human LRRC4 protein (Recombinant) (C-His) (STJP001209)	HEK293 cells
STJP001384	Human VSIG4 protein (Recombinant) (C-His) (STJP001384)	HEK293 cells
STJP002429	Human Lactotransferrin protein (Recombinant) (C-His) (STJP002429)	HEK293 cells
STJP001083	Human CD83 protein (Recombinant) (C-His) (STJP001083)	HEK293 cells
STJP000933	Human CD5 protein (Recombinant) (C-His) (STJP000933)	HEK293 cells
STJP000799	Human UBE2L3 protein (Recombinant) (C-His) (STJP000799)	E. coli

Human LILRA3/CD85e protein (Recombinant) (C-His) (STJP001323)