• Biotinylated Human LILRA3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human LILRA3 is greater than 95% as determined by SEC-HPLC.

Human LILRA3/CD85e protein (Recombinant) (C-His-Avi) {Biotin} (STJP001688)

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STJP001688

£618.50 - £1,909.50
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human LILRA3/CD85e-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: LILRA3
Gene ID: 11026
Uniprot ID: LIRA3_HUMAN
Immunogen Region: Gly24-Glu439
Immunogen: DNA sequence encoding Human LILRA3/CD85e including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Post Translational Modifications N-glycosylation is required for ligand binding.
Function Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3
Cd85 Antigen-Like Family Member E
Immunoglobulin-Like Transcript 6
Ilt-6
Leukocyte Immunoglobulin-Like Receptor 4
Lir-4
Monocyte Inhibitory Receptor Hm43/Hm31
Cd Antigen Cd85e
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Protein Names Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 3 protein
Cd85 Antigen-Like Family Member E protein
Immunoglobulin-Like Transcript 6 protein
Ilt-6 protein
Leukocyte Immunoglobulin-Like Receptor 4 protein
Lir-4 protein
Monocyte Inhibitory Receptor Hm43/Hm31 protein
Cd Antigen Cd85e protein
LILRA3 protein
ILT6 protein
LIR4 protein

Information sourced from Uniprot.org

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