Host: |
HEK293 cells |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
Immunoreactivity: |
1.Measured by its binding ability in a functional ELISA.Immobilized Human CD2 at 2 Mu g/mL (100 Mu L/well) can bind Human CD58 with a linear range of 1.22-34.4 ng/mL.|2.Measured by its binding ability in a functional ELISA. Immobilized CD58 (LFA-3) M |
Gene Symbol: |
CD58 |
Gene ID: |
965 |
Uniprot ID: |
LFA3_HUMAN |
Immunogen: |
Recombinant Human LFA-3/CD58 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Phe 29-Arg 215 ) of human CD58 (Accession #BC005930) fused with an Fc, 6×His tag at the C-terminus. |
Immunogen Sequence: |
FSQQIYGVVYGNVTFHVPSN VPLKEVLWKKQKDKVAELEN SEFRAFSSFKNRVYLDTVSG SLTIYNLTSSDEDEYEMESP NITDTMKFFLYVLESLPSPT LTCALTNGSIEVQCMIPEYY NSHRGLIMYSWDCPMEQCKR NSTSIYFKMENDLPQKIQCT LSNPLFNTTSSIILTTCIPS SGHSRHR |
Protein Name | Lymphocyte Function-Associated Antigen 3Ag3Surface Glycoprotein Lfa-3Cd Antigen Cd58 |
Database Links | Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Lymphocyte Function-Associated Antigen 3 proteinAg3 proteinSurface Glycoprotein Lfa-3 proteinCd Antigen Cd58 proteinCD58 proteinLFA3 protein |
Information sourced from Uniprot.org