Human LETMD1 protein (Recombinant) (N-His) (STJP005587)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LETMD1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | LETMD1 |
| Gene ID | 25875 |
| Uniprot ID | LTMD1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Pro162-Asn347 |
Additional Info
| Function | Plays an essential role for mitochondrial structure and function, as well as thermogenesis of brown adipocytes. In brown adipose tissue also localizes in the nucleus where it interacts with the chromatin remodeler SMARCA4 to regulate thermogenic genes expression, such as UCP1. May regulate phagocytosis and inflammatory responses to lipopolysaccharide in macrophages. Involved in tumorigenesis and may function as a negative regulator of the p53/TP53. |
| Protein Name | Letm1 Domain-Containing Protein 1Cervical Cancer 1 Proto-Oncogene Protein P40Cervical Cancer Proto-Oncogene 2 ProteinHccr-1Hcrr-2 |
| Database Links | |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane ProteinNucleusMitochondrion Inner Membrane |
| Alternative Protein Names | Letm1 Domain-Containing Protein 1 proteinCervical Cancer 1 Proto-Oncogene Protein P40 proteinCervical Cancer Proto-Oncogene 2 Protein proteinHccr-1 proteinHcrr-2 proteinLETMD1 protein |
Information sourced from Uniprot.org