Human LETMD1 protein (Recombinant) (N-His) (STJP005587)

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STJP005587
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LETMD1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: LETMD1
Gene ID: 25875
Uniprot ID: LTMD1_HUMAN
Immunogen Region: Pro162-Asn347
Immunogen: Homo sapiens (Human)
Function Plays an essential role for mitochondrial structure and function, as well as thermogenesis of brown adipocytes. In brown adipose tissue also localizes in the nucleus where it interacts with the chromatin remodeler SMARCA4 to regulate thermogenic genes expression, such as UCP1. May regulate phagocytosis and inflammatory responses to lipopolysaccharide in macrophages. Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.
Protein Name Letm1 Domain-Containing Protein 1
Cervical Cancer 1 Proto-Oncogene Protein P40
Cervical Cancer Proto-Oncogene 2 Protein
Hccr-1
Hcrr-2
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Nucleus
Mitochondrion Inner Membrane
Alternative Protein Names Letm1 Domain-Containing Protein 1 protein
Cervical Cancer 1 Proto-Oncogene Protein P40 protein
Cervical Cancer Proto-Oncogene 2 Protein protein
Hccr-1 protein
Hcrr-2 protein
LETMD1 protein

Information sourced from Uniprot.org

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