Human LAP3 protein (Recombinant) (His-Tag) (STJP019116)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP019116
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General Information

Short DescriptionRecombinant-Human LAP3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.5) containing 50% Glycerol, 5mM DTT, 1mM EDTA
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolLAP3
Gene ID51056
Uniprot IDAMPL_HUMAN
Accession NumberNP_056991.2
ImmunogenHuman
Immunogen Region1-519aa
Immunogen Sequence MFLLPLPAAG RVVVRRLAVR RFGSRSLSTA DMTKGLVLGI YSKEKEDDVP QFTSAGENFD KLLAGKLRET LNISGPPLKA GKTRTFYGLH QDFPSVVLVG LGKKAAGIDE QENWHEGKEN IRAAVAAGCR QIQDLELSSV EVDPCGDAQA AAEGAVLGLY EYDDLKQKKK MAVSAKLYGS GDQEAWQKGV LFASGQNLAR QLMETP

Additional Info

Function Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.
Protein Name Cytosol Aminopeptidase
Cysteinylglycine-S-Conjugate Dipeptidase
Leucine Aminopeptidase 3
Lap-3
Leucyl Aminopeptidase
Peptidase S
Proline Aminopeptidase
Prolyl Aminopeptidase
Database Links
Cellular Localisation Cytoplasm
Alternative Protein Names Cytosol Aminopeptidase protein
Cysteinylglycine-S-Conjugate Dipeptidase protein
Leucine Aminopeptidase 3 protein
Lap-3 protein
Leucyl Aminopeptidase protein
Peptidase S protein
Proline Aminopeptidase protein
Prolyl Aminopeptidase protein
LAP3 protein
LAPEP protein
PEPS protein

Information sourced from Uniprot.org

Citations

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