Human LANCL1 protein (Recombinant) (His-Tag) (STJP018832)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018832
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General Information

Short DescriptionRecombinant-Human LANCL1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 7.5) containing 0.15M NaCl, 20% Glycerol, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolLANCL1
Gene ID10314
Uniprot IDLANC1_HUMAN
Accession NumberNP_006046
ImmunogenHuman
Immunogen Region1-399aa
Immunogen SequenceMAQRAFP NPYADYNKSL AEGYFDAAGR LTPEFSQRLT NKIRELLQQM ERGLKSADPR DGTGYTGWAG IAVLYLHLYD VFGDPAYLQL AHGYVKQSLN CLTKRSITFL CGDAGPLAVA AVLYHKMNNE KQAEDCITRL IHLNKIDPHA PNEMLYGRIG YIYALLFVNK NFGVEKIPQS HIQQICETIL TSGENLARKR NFTAKS

Additional Info

Tissue Specificity Detected in erythrocytes, brain, kidney, testis, ovary, heart, lung, placenta and spleen (at protein level). Ubiquitous. Strongly expressed in brain, spinal cord, pituitary gland, kidney, heart, skeletal muscle, pancreas, ovary and testis.
Function Functions as a glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione.
Protein Name Glutathione S-Transferase Lancl1
40 Kda Erythrocyte Membrane Protein
P40
Lanc-Like Protein 1
Database Links
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Alternative Protein Names Glutathione S-Transferase Lancl1 protein
40 Kda Erythrocyte Membrane Protein protein
P40 protein
Lanc-Like Protein 1 protein
LANCL1 protein
GPR69A protein

Information sourced from Uniprot.org

Citations

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