| Tissue Specificity | Detected in erythrocytes, brain, kidney, testis, ovary, heart, lung, placenta and spleen (at protein level). Ubiquitous. Strongly expressed in brain, spinal cord, pituitary gland, kidney, heart, skeletal muscle, pancreas, ovary and testis. |
| Function | Functions as a glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione. |
| Protein Name | Glutathione S-Transferase Lancl140 Kda Erythrocyte Membrane ProteinP40Lanc-Like Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane Protein |
| Alternative Protein Names | Glutathione S-Transferase Lancl1 protein40 Kda Erythrocyte Membrane Protein proteinP40 proteinLanc-Like Protein 1 proteinLANCL1 proteinGPR69A protein |
Information sourced from Uniprot.org