| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.26ng/mL |
| Detection Limit: | 0.781-50ng/mL |
| Short Description : | This LAMC2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | LAMC2 |
| Gene ID: | 3918 |
| Uniprot ID: | LAMC2_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | The large variant is expressed only in specific epithelial cells of embryonic and neonatal tissues. In 17-week old embryo the small variant is found in cerebral cortex, lung, and distal tubes of kidney, but not in epithelia except for distal tubuli. |
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate (CS). CS attachment is on either Ser-803 or Ser-805. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. |
| Protein Name | Laminin Subunit Gamma-2 Cell-Scattering Factor 140 Kda Subunit Csf 140 Kda Subunit Epiligrin Subunit Gamma Kalinin Subunit Gamma Kalinin/Nicein/Epiligrin 100 Kda Subunit Ladsin 140 Kda Subunit Laminin B2t Chain Laminin-5 Subunit Gamma Large Adhesive Scatter Factor 140 Kda Subunit Nicein Subunit Gamma |
| Database Links | Reactome: R-HSA-1474228 Reactome: R-HSA-2022090 Reactome: R-HSA-2214320 Reactome: R-HSA-3000157 Reactome: R-HSA-3000171 Reactome: R-HSA-446107 Reactome: R-HSA-8874081 |
| Cellular Localisation | Secreted Extracellular Space Extracellular Matrix Basement Membrane Major Component |
| Alternative ELISA Names | Laminin Subunit Gamma-2 ELISA kit Cell-Scattering Factor 140 Kda Subunit ELISA kit Csf 140 Kda Subunit ELISA kit Epiligrin Subunit Gamma ELISA kit Kalinin Subunit Gamma ELISA kit Kalinin/Nicein/Epiligrin 100 Kda Subunit ELISA kit Ladsin 140 Kda Subunit ELISA kit Laminin B2t Chain ELISA kit Laminin-5 Subunit Gamma ELISA kit Large Adhesive Scatter Factor 140 Kda Subunit ELISA kit Nicein Subunit Gamma ELISA kit LAMC2 ELISA kit LAMB2T ELISA kit LAMNB2 ELISA kit |
| output |
Information sourced from Uniprot.org