Human LAGE3 protein (Recombinant) (N-GST & C-His) (STJP016273)

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STJP016273
£222.50 - £1,177.50
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LAGE3-N-GST & C-His protein was developed from e.coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: LAGE3
Gene ID: 8270
Uniprot ID: LAGE3_HUMAN
Immunogen Region: Met58-Arg143
Immunogen: Homo sapiens (Human)
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.
Protein Name Ekc/Keops Complex Subunit Lage3
L Antigen Family Member 3
Protein Eso-3
Protein Itba2
Database Links Reactome: R-HSA-6782315
Cellular Localisation Cytoplasm
Nucleus
Alternative Protein Names Ekc/Keops Complex Subunit Lage3 protein
L Antigen Family Member 3 protein
Protein Eso-3 protein
Protein Itba2 protein
LAGE3 protein
DXS9879E protein
ESO3 protein
ITBA2 protein

Information sourced from Uniprot.org