Human Lactate Dehydrogenase B/LDHB protein (Recombinant) (No-Tag) (STJP019278)

Name: Human Lactate Dehydrogenase B/LDHB protein (Recombinant) (No-Tag) (STJP019278)
SKU: STJP019278
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP019278

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Short Description	Recombinant-Human Lactate Dehydrogenase B/LDHB-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications.
Applications	SDS-PAGE/Enzyme Activity
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity	Specific activity is > 300unit/mg, in which one unit will convert 1.0 umole of pyruvate to L-lactate and beta-NAD per minute at pH 7.5 at 37C.

Gene Symbol	LDHB
Gene ID	3945
Uniprot ID	LDHB_HUMAN
Accession Number	NP_002291
Immunogen	Human
Immunogen Region	1-334aa
Immunogen Sequence	MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENW

Tissue Specificity	Predominantly expressed in aerobic tissues such as cardiac muscle.
Function	Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
Protein Name	L-Lactate Dehydrogenase B Chain Ldh-B Ldh Heart Subunit Ldh-H Renal Carcinoma Antigen Ny-Ren-46
Database Links	Reactome: R-HSA-70268
Cellular Localisation	Cytoplasm Mitochondrion Inner Membrane Peripheral Membrane Protein
Alternative Protein Names	L-Lactate Dehydrogenase B Chain protein Ldh-B protein Ldh Heart Subunit protein Ldh-H protein Renal Carcinoma Antigen Ny-Ren-46 protein LDHB protein

Information sourced from Uniprot.org