Human Lactate Dehydrogenase B/LDHB protein (Recombinant) (His-Tag) (STJP016756)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Lactate Dehydrogenase B/LDHB-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity | Specific activity is > 300unit/mg, in which one unit will convert 1.0 umole of pyruvate to L-lactate and beta-NAD per minute at pH 7.5 at 37C. |
Target Information
| Gene Symbol | LDHB |
| Gene ID | 3945 |
| Uniprot ID | LDHB_HUMAN |
| Accession Number | NP_002291.1 |
| Immunogen | Human |
| Immunogen Region | 1-334aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Predominantly expressed in aerobic tissues such as cardiac muscle. |
| Function | Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+). |
| Protein Name | L-Lactate Dehydrogenase B ChainLdh-BLdh Heart SubunitLdh-HRenal Carcinoma Antigen Ny-Ren-46 |
| Database Links | Reactome: R-HSA-70268 |
| Cellular Localisation | CytoplasmMitochondrion Inner MembranePeripheral Membrane Protein |
| Alternative Protein Names | L-Lactate Dehydrogenase B Chain proteinLdh-B proteinLdh Heart Subunit proteinLdh-H proteinRenal Carcinoma Antigen Ny-Ren-46 proteinLDHB protein |
Information sourced from Uniprot.org