| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Supplied as a 0.22 Mu m filtered solution in 20mM Tris, 250mM NaCl, 10% Glycerol, pH 8.0. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <1 EU/Mu g |
| Gene Symbol: | LDHA |
| Gene ID: | 3939 |
| Uniprot ID: | LDHA_HUMAN |
| Immunogen Region: | Met1-Phe332 |
| Immunogen: | Recombinant Human Lactate Dehydrogenase A/LDHA Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Phe332) of human Lactate Dehydrogenase A/LDHA (Accession #NP_005557.1) fused with a 6×His tag |
| Immunogen Sequence: | QSYSIYENYGNIKEFNATHA AFEYSKSIGGTPALDRRVQD VNDTISDVKQKWRCVVYPGN GFVSASIFGFQAEVGPNNTR SIRKFNTMRQCIDFTFSDVI NIDIYNPCIAPNINNTECQF LKSVL |
| Tissue Specificity | Predominantly expressed in anaerobic tissues such as skeletal muscle and liver. |
| Post Translational Modifications | ISGylated. |
| Function | Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+). |
| Protein Name | L-Lactate Dehydrogenase A ChainLdh-ACell Proliferation-Inducing Gene 19 ProteinLdh Muscle SubunitLdh-MRenal Carcinoma Antigen Ny-Ren-59 |
| Database Links | Reactome: R-HSA-70268Reactome: R-HSA-9861718 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | L-Lactate Dehydrogenase A Chain proteinLdh-A proteinCell Proliferation-Inducing Gene 19 Protein proteinLdh Muscle Subunit proteinLdh-M proteinRenal Carcinoma Antigen Ny-Ren-59 proteinLDHA proteinPIG19 protein |
Information sourced from Uniprot.org