Human KRT2 protein (Recombinant) (N-His) (STJP004634)

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STJP004634
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human KRT2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: KRT2
Gene ID: 3849
Uniprot ID: K22E_HUMAN
Immunogen Region: Cys7-Leu160
Immunogen: Homo sapiens (Human)
Function Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins. Plays a role in the establishment of the epidermal barrier on plantar skin.
Protein Name Keratin - Type Ii Cytoskeletal 2 Epidermal
Cytokeratin-2e
Ck-2e
Epithelial Keratin-2e
Keratin-2 Epidermis
Keratin-2e
K2e
Type-Ii Keratin Kb2
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cytoplasm
Alternative Protein Names Keratin - Type Ii Cytoskeletal 2 Epidermal protein
Cytokeratin-2e protein
Ck-2e protein
Epithelial Keratin-2e protein
Keratin-2 Epidermis protein
Keratin-2e protein
K2e protein
Type-Ii Keratin Kb2 protein
KRT2 protein
KRT2A protein
KRT2E protein

Information sourced from Uniprot.org

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