| Short Description : | Recombinant-Human KRT16-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KRT16 |
| Gene ID: | 3868 |
| Uniprot ID: | K1C16_HUMAN |
| Accession Number: | NP_005548 |
| Immunogen: | Human |
| Immunogen Region: | 1-473aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMTTCSRQ FTSSSSMKGS CGIGGGIGGG SSRISSVLAG GSCRAPSTYG GGLSVSSRFS SGGACGLGGG YGGGFSSSSS FGSGFGGGYG GGLGAGFGGG LGAGFGGGFA GGDGLLVGSE KVTMQNLNDR LASYLDKVRA LEEANADLEV KIRDWYQRQR PSEIKDYSPY FKTIEDLRNK IIAATIENAQ PILQIDNARL AADDFRTK |
| Tissue Specificity | Expressed in the corneal epithelium (at protein level). |
| Function | Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. |
| Protein Name | Keratin - Type I Cytoskeletal 16Cytokeratin-16Ck-16Keratin-16K16 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Protein Names | Keratin - Type I Cytoskeletal 16 proteinCytokeratin-16 proteinCk-16 proteinKeratin-16 proteinK16 proteinKRT16 proteinKRT16A protein |
Information sourced from Uniprot.org