| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human KRT1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | KRT1 |
| Gene ID: | 3848 |
| Uniprot ID: | K2C1_HUMAN |
| Immunogen Region: | Glu370-Glu489 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Undergoes deimination of some arginine residues (citrullination). |
| Function | May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. |
| Protein Name | Keratin - Type Ii Cytoskeletal 167 Kda CytokeratinCytokeratin-1Ck-1Hair Alpha ProteinKeratin-1K1Type-Ii Keratin Kb1 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9725554 |
| Cellular Localisation | Cell MembraneCytoplasm |
| Alternative Protein Names | Keratin - Type Ii Cytoskeletal 1 protein67 Kda Cytokeratin proteinCytokeratin-1 proteinCk-1 proteinHair Alpha Protein proteinKeratin-1 proteinK1 proteinType-Ii Keratin Kb1 proteinKRT1 proteinKRTA protein |
Information sourced from Uniprot.org