Human KLRG1/CLEC15A protein (Recombinant) (C-His) (STJP009506)

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STJP009506
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human KLRG1/CLEC15A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: KLRG1
Gene ID: 10219
Uniprot ID: KLRG1_HUMAN
Immunogen Region: Ser74-Lys186
Immunogen: Homo sapiens (Human)
Function Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Protein Name Killer Cell Lectin-Like Receptor Subfamily G Member 1
C-Type Lectin Domain Family 15 Member A
Itim-Containing Receptor Mafa-L
Mafa-Like Receptor
Mast Cell Function-Associated Antigen
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Killer Cell Lectin-Like Receptor Subfamily G Member 1 protein
C-Type Lectin Domain Family 15 Member A protein
Itim-Containing Receptor Mafa-L protein
Mafa-Like Receptor protein
Mast Cell Function-Associated Antigen protein
KLRG1 protein
CLEC15A protein
MAFA protein
MAFAL protein

Information sourced from Uniprot.org

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