| Function | Has a plus-end-directed microtubule motor activity and functions as a motor for transport of vesicles and organelles along microtubules. Isoform 2: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde synaptic vesicle transport along axonal microtubules from the cell body to the presynapse in neuronal cells. Functions as a downstream effector in a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells. Isoform 3: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde transport of mitochondria. |
| Protein Name | Kinesin-Like Protein Kif1bKlp |
| Database Links | Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonHas A Plus-End-Directed Microtubule Motor Activity And Therefore Associates With MicrotubulesIsoform 2: Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneAssociates With Synaptic Vesicles And Mediates Their Anterograde Transport Along Axonal MicrotubulesIsoform 3: MitochondrionAssociates With Mitochondria And Mediates Their Movement Along Microtubules |
| Alternative Protein Names | Kinesin-Like Protein Kif1b proteinKlp proteinKIF1B proteinKIAA0591 proteinKIAA1448 protein |
Information sourced from Uniprot.org
