Human KIF1B protein (Recombinant) (N-His) (STJP007999)

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STJP007999
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Short Description :Recombinant-Human KIF1B-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:KIF1B
Gene ID:23095
Uniprot ID:KIF1B_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Glu287
Function Has a plus-end-directed microtubule motor activity and functions as a motor for transport of vesicles and organelles along microtubules. Isoform 2: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde synaptic vesicle transport along axonal microtubules from the cell body to the presynapse in neuronal cells. Functions as a downstream effector in a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells. Isoform 3: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde transport of mitochondria.
Protein Name Kinesin-Like Protein Kif1b
Klp
Database Links Reactome: R-HSA-6811434
Reactome: R-HSA-983189
Cellular Localisation Cytoplasm
Cytoskeleton
Has A Plus-End-Directed Microtubule Motor Activity And Therefore Associates With Microtubules
Isoform 2: Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Associates With Synaptic Vesicles And Mediates Their Anterograde Transport Along Axonal Microtubules
Isoform 3: Mitochondrion
Associates With Mitochondria And Mediates Their Movement Along Microtubules
Alternative Protein Names Kinesin-Like Protein Kif1b protein
Klp protein
KIF1B protein
KIAA0591 protein
KIAA1448 protein

Information sourced from Uniprot.org