Human KDM4D protein (Recombinant) (N-His) (STJP007503)

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STJP007503
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human KDM4D-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: KDM4D
Gene ID: 55693
Uniprot ID: KDM4D_HUMAN
Immunogen Region: Asn17-Ala354
Immunogen: Homo sapiens (Human)
Function Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Protein Name Lysine-Specific Demethylase 4d
Jmjc Domain-Containing Histone Demethylation Protein 3d
Jumonji Domain-Containing Protein 2d
Histone H3-Trimethyl-L-Lysine(9 Demethylase 4d
Database Links Reactome: R-HSA-3214842
Cellular Localisation Nucleus
Alternative Protein Names Lysine-Specific Demethylase 4d protein
Jmjc Domain-Containing Histone Demethylation Protein 3d protein
Jumonji Domain-Containing Protein 2d protein
Histone H3-Trimethyl-L-Lysine(9 Demethylase 4d protein
KDM4D protein
JHDM3D protein
JMJD2D protein

Information sourced from Uniprot.org